Download PDF 31 downloads
Abstract
Introduction Irritable bowel syndrome (IBS) is a complex and multifaceted disorder characterized by recurrent abdominal pain, discomfort, and altered bowel habits, in the absence of any identifiable organic cause. (Alsolami2023)Despite its high prevalence and significant impact on quality of life, the precise etiology of IBS remains elusive. However, emerging research points to a crucial role of the gutbrain axis (GBA) in the pathophysiology of IBS, with serotonin (5- hydroxytryptamine or 5-HT) signaling playing a key part in this bidirectional communication network. This meta-analysis aims to delve into the intricacies of the GBA and serotonin signaling in IBS, focusing specifically on the interactions between gut microbiota and metabolites. (Mishima & Ishihara, 2021)(Vahora et al., 2020)(Bruta et al.2021)(Guzel & Mirowska-Guzel, 2022)(Kanova & Kohout, 2021)(Chen et al.2022)(Koopman et al.2021)(Tao et al.2022)(Bi et al.2021)(Bellini et al.2021)
How to cite
The Gut-Brain Axis and Serotonin Signalling in Irritable Bowel Syndrome: A Meta-Analysis of Gut Microbiota and Metabolite Interactions. (2024). EIU Journals. https://journals.eiu.ac/article/the-gut-brain-axis-and-serotonin-signalling-in-irritable-bowel-syndrome-a-meta-analysis-of-gut-microbiota-and-metabolite-interactions/
"The Gut-Brain Axis and Serotonin Signalling in Irritable Bowel Syndrome: A Meta-Analysis of Gut Microbiota and Metabolite Interactions." EIU Journals, 2024, https://journals.eiu.ac/article/the-gut-brain-axis-and-serotonin-signalling-in-irritable-bowel-syndrome-a-meta-analysis-of-gut-microbiota-and-metabolite-interactions/.
@article{eiu2024the,
title = {The Gut-Brain Axis and Serotonin Signalling in Irritable Bowel Syndrome: A Meta-Analysis of Gut Microbiota and Metabolite Interactions},
journal = {EIU Journals},
year = {2024},
url = {https://journals.eiu.ac/article/the-gut-brain-axis-and-serotonin-signalling-in-irritable-bowel-syndrome-a-meta-analysis-of-gut-microbiota-and-metabolite-interactions/}
}